Rotavirus is a contagious virus that commonly causes diarrhea in small children. Worldwide, it is the leading cause of diarrhoea-associated morbidity and mortality in children aged 5 years and younger1. Rotavirus can be easily passed around through contact with an infected person’s stool2. Hilleman Laboratories is developing a heat stable rotavirus vaccine technology. Pre-clinical development has been completed and the project is currently in Phase II clinical development. The technology has been out-licensed.
1 Troeger C, Khalil IA, Rao PC, Cao S, Blacker BF, Ahmed T, Armah G, Bines JE, Brewer TG, Colombara DV, Kang G, Kirkpatrick BD, Kirkwood CD, Mwenda JM, Parashar UD, Petri WA Jr, Riddle MS, Steele AD, Thompson RL, Walson JL, Sanders JW, Mokdad AH, Murray CJL, Hay SI, Reiner RC Jr. Rotavirus Vaccination and the Global Burden of Rotavirus Diarrhea Among Children Younger Than 5 Years. JAMA Pediatr. 2018 Oct 1;172(10):958-965. doi: 10.1001/jamapediatrics.2018.1960. PMID: 30105384; PMCID: PMC6233802. Accessed: 27 October 2021
2 Crawford SE, Ramani S, Tate JE, Parashar UD, Svensson L, Hagbom M, Franco MA, Greenberg HB, O'Ryan M, Kang G, Desselberger U, Estes MK. Rotavirus infection. Nat Rev Dis Primers. 2017 Nov 9;3:17083. doi: 10.1038/nrdp.2017.83. PMID: 29119972; PMCID: PMC5858916. Accessed: 27 October 2021